A painful chancre originating as a papule and then evolving into a nodule at the primary fly bite site, ( Early stage ).
Cachexia, somnolence and central nervous system signs.

 It is a disease caused by protozoan trypanosoma sp. which caused sleeping sickness.

        SIGNs  AND  SYMPTOMs
  Fever, headache, insomnia, anaemia, rashes, local oedema,
  Enlargement of the lymph nodes,
  Painless lymphadenopathy,
  Hydrocele

              TRANSMISSION
 By the bite of an infected tsetse fly.

         CAUSATIVE  AGENT
 Trypanosoma brucei gambiense,
 Trypanosoma brucei Rhodesiense.

          INCUBATION  PERIOD
3 days ---- 3 weeks but may be about 6 years.

                  RESERVOIR
               B Man ( human)

     PREVENTION  AND CONTROL

1. Use of insecticide,
2. Treatment of an infected person,
3. Use of skin protector,
4. Use of treating net
5. Health education